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Antidepressent Effect of Two New Benzyl Derivatives from Wild Strawberry Fragaria vesca var. nubicola Lindl. ex Hook.f.

Overview of attention for article published in Frontiers in Pharmacology, July 2017
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Title
Antidepressent Effect of Two New Benzyl Derivatives from Wild Strawberry Fragaria vesca var. nubicola Lindl. ex Hook.f.
Published in
Frontiers in Pharmacology, July 2017
DOI 10.3389/fphar.2017.00469
Pubmed ID
Authors

Sadia Naz, Umar Farooq, Ajmal Khan, Haroon Khan, Nasiara Karim, Rizwana Sarwar, Javid Hussain, Abdur Rauf

Abstract

Two new benzyl derivatives were isolated from ethyl acetate fraction of wild strawberry, Fragaria vesca var. nubicola Lindl. ex Hook.f. The structures of these compounds were elucidated to be 5-(4-hydroxy-3-methoxyphenethyl)-7-methoxy-2H-chromen-3-ol (1) and 5-(4-hydroxy-3-methoxyphenethyl)-4,7-dimethoxy-2H-chromen-3-ol (2) based on spectroscopic data through IR, UV, (1)H-NMR, (13)C-NMR along with two dimensional (2D) techniques HMBC, HMQC, and COSY. Both compounds 1 and 2 were studied in tail suspension and forced swim tests for antidepressant like effects. A significant dose dependent antidepressant like effect was observed by causing spontaneous anti-immobility at various test doses upon intraperitoneal administration.

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X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Other 2 12%
Student > Bachelor 2 12%
Lecturer > Senior Lecturer 1 6%
Lecturer 1 6%
Student > Doctoral Student 1 6%
Other 3 18%
Unknown 7 41%
Readers by discipline Count As %
Chemistry 3 18%
Agricultural and Biological Sciences 2 12%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Computer Science 1 6%
Biochemistry, Genetics and Molecular Biology 1 6%
Other 2 12%
Unknown 7 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2018.
All research outputs
#13,562,649
of 22,990,068 outputs
Outputs from Frontiers in Pharmacology
#4,123
of 16,283 outputs
Outputs of similar age
#161,242
of 316,990 outputs
Outputs of similar age from Frontiers in Pharmacology
#71
of 256 outputs
Altmetric has tracked 22,990,068 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,283 research outputs from this source. They receive a mean Attention Score of 5.0. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,990 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 256 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.