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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Anticancer Activities of Surfactin and Potential Application of Nanotechnology Assisted Surfactin Delivery
|
|---|---|
| Published in |
Frontiers in Pharmacology, October 2017
|
| DOI | 10.3389/fphar.2017.00761 |
| Pubmed ID | |
| Authors |
Yuan-Seng Wu, Siew-Ching Ngai, Bey-Hing Goh, Kok-Gan Chan, Learn-Han Lee, Lay-Hong Chuah |
| Abstract |
Surfactin, a cyclic lipopeptide biosurfactant produced by various strains of Bacillus genus, has been shown to induce cytotoxicity against many cancer types, such as Ehrlich ascites, breast and colon cancers, leukemia and hepatoma. Surfactin treatment can inhibit cancer progression by growth inhibition, cell cycle arrest, apoptosis, and metastasis arrest. Owing to the potent effect of surfactin on cancer cells, numerous studies have recently investigated the mechanisms that underlie its anticancer activity. The amphiphilic nature of surfactin allows its easy incorporation nano-formulations, such as polymeric nanoparticles, micelles, microemulsions, liposomes, to name a few. The use of nano-formulations offers the advantage of optimizing surfactin delivery for an improved anticancer therapy. This review focuses on the current knowledge of surfactin properties and biosynthesis; anticancer activity against different cancer models and the underlying mechanisms involved; as well as the potential application of nano-formulations for optimal surfactin delivery. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 232 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 232 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 32 | 14% |
| Student > Ph. D. Student | 31 | 13% |
| Researcher | 21 | 9% |
| Student > Doctoral Student | 11 | 5% |
| Student > Bachelor | 10 | 4% |
| Other | 34 | 15% |
| Unknown | 93 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 45 | 19% |
| Agricultural and Biological Sciences | 18 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 11 | 5% |
| Chemistry | 10 | 4% |
| Engineering | 10 | 4% |
| Other | 29 | 13% |
| Unknown | 109 | 47% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2023.
All research outputs
#6,967,195
of 26,011,622 outputs
Outputs from Frontiers in Pharmacology
#3,033
of 20,086 outputs
Outputs of similar age
#102,966
of 341,561 outputs
Outputs of similar age from Frontiers in Pharmacology
#38
of 276 outputs
Altmetric has tracked 26,011,622 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 20,086 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,561 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 276 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.