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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Poly(Ethylene Glycol)–Polylactide Micelles for Cancer Therapy
|
|---|---|
| Published in |
Frontiers in Pharmacology, March 2018
|
| DOI | 10.3389/fphar.2018.00202 |
| Pubmed ID | |
| Authors |
Jixue Wang, Shengxian Li, Yuping Han, Jingjing Guan, Shirley Chung, Chunxi Wang, Di Li |
| Abstract |
For the treatment of malignancy, many therapeutic agents, including small molecules, photosensitizers, immunomodulators, proteins and genes, and so forth, have been loaded into nanocarriers for controllable cancer therapy. Among these nanocarriers, polymeric micelles have been considered as one of the most promising nanocarriers, some of which have already been applied in different stages of clinical trials. The successful advantages of polymeric micelles from bench to bedside are due to their special core/shell structures, which can carry specific drugs in certain disease conditions. Particularly, poly(ethylene glycol)-polylactide (PEG-PLA) micelles have been considered as one of the most promising platforms for drug delivery. The PEG shell effectively prevents the adsorption of proteins and phagocytes, thereby evidently extending the blood circulation period. Meanwhile, the hydrophobic PLA core can effectively encapsulate many therapeutic agents. This review summarizes recent advances in PEG-PLA micelles for the treatment of malignancy. In addition, future perspectives for the development of PEG-PLA micelles as drug delivery systems are also presented. |
X Demographics
The data shown below were collected from the profiles of 44 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 5% |
| India | 2 | 5% |
| Switzerland | 2 | 5% |
| Mexico | 2 | 5% |
| Brazil | 2 | 5% |
| Argentina | 1 | 2% |
| Venezuela, Bolivarian Republic of | 1 | 2% |
| Côte d'Ivoire | 1 | 2% |
| Nigeria | 1 | 2% |
| Other | 5 | 11% |
| Unknown | 25 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 31 | 70% |
| Scientists | 9 | 20% |
| Practitioners (doctors, other healthcare professionals) | 4 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 143 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 143 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 14% |
| Student > Bachelor | 20 | 14% |
| Student > Master | 16 | 11% |
| Student > Doctoral Student | 8 | 6% |
| Student > Postgraduate | 7 | 5% |
| Other | 18 | 13% |
| Unknown | 54 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 24 | 17% |
| Pharmacology, Toxicology and Pharmaceutical Science | 22 | 15% |
| Biochemistry, Genetics and Molecular Biology | 13 | 9% |
| Engineering | 8 | 6% |
| Materials Science | 4 | 3% |
| Other | 15 | 10% |
| Unknown | 57 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 27. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2020.
All research outputs
#1,440,587
of 25,540,105 outputs
Outputs from Frontiers in Pharmacology
#546
of 19,906 outputs
Outputs of similar age
#31,554
of 348,939 outputs
Outputs of similar age from Frontiers in Pharmacology
#22
of 370 outputs
Altmetric has tracked 25,540,105 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 19,906 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 348,939 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 370 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.