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The Multifaceted Effects of Alpha1-Antitrypsin on Neutrophil Functions

Overview of attention for article published in Frontiers in Pharmacology, April 2018
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  • Good Attention Score compared to outputs of the same age and source (71st percentile)

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134 Mendeley
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Title
The Multifaceted Effects of Alpha1-Antitrypsin on Neutrophil Functions
Published in
Frontiers in Pharmacology, April 2018
DOI 10.3389/fphar.2018.00341
Pubmed ID
Authors

Sabina Janciauskiene, Sabine Wrenger, Stephan Immenschuh, Beata Olejnicka, Timm Greulich, Tobias Welte, Joanna Chorostowska-Wynimko

Abstract

Neutrophils are the predominant immune cells in human blood possessing heterogeneity, plasticity and functional diversity. The activation and recruitment of neutrophils into inflamed tissue in response to stimuli are tightly regulated processes. Alpha1-Antitrypsin (AAT), an acute phase protein, is one of the potent regulators of neutrophil activation via both -protease inhibitory and non-inhibitory functions. This review summarizes our current understanding of the effects of AAT on neutrophils, illustrating the interplay between AAT and the key effector functions of neutrophils.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 134 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 134 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 20 15%
Researcher 18 13%
Student > Ph. D. Student 17 13%
Student > Master 14 10%
Student > Doctoral Student 9 7%
Other 11 8%
Unknown 45 34%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 25 19%
Medicine and Dentistry 16 12%
Pharmacology, Toxicology and Pharmaceutical Science 13 10%
Agricultural and Biological Sciences 10 7%
Immunology and Microbiology 6 4%
Other 13 10%
Unknown 51 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2023.
All research outputs
#15,077,372
of 26,213,016 outputs
Outputs from Frontiers in Pharmacology
#4,641
of 20,173 outputs
Outputs of similar age
#172,818
of 344,344 outputs
Outputs of similar age from Frontiers in Pharmacology
#109
of 395 outputs
Altmetric has tracked 26,213,016 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 20,173 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,344 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 395 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.