Title |
Eventual Role of Asymptomatic Cases of Dengue for the Introduction and Spread of Dengue Viruses in Non-Endemic Regions
|
---|---|
Published in |
Frontiers in Physiology, January 2012
|
DOI | 10.3389/fphys.2012.00070 |
Pubmed ID | |
Authors |
Claude Chastel |
Abstract |
In dengue virus infections the asymptomatic cases are much more frequent than the symptomatic ones, but their true role in the introduction and subsequent spread of dengue viruses in non-endemic regions remains to de clarified. We analyzed data from English and French literatures to assess if viremia in asymptomatic dengue infections might be sufficient to represent a true risk. During outbreaks of dengue a large number of individuals are infected and since viremia levels in symptomatic patients are known to vary by many orders of magnitude, it is reasonable to augur that a proportion of asymptomatic cases might reach levels of viremia sufficient to infect competent mosquitoes. In addition, a number of new ways of contamination in man by dengue viruses were recently described such as blood transfusion, bone marrow transplantation, and nosocomial infections that may be worth considering. |
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Geographical breakdown
Country | Count | As % |
---|---|---|
Thailand | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 4% |
Mexico | 1 | <1% |
Unknown | 113 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 26 | 22% |
Student > Master | 13 | 11% |
Student > Ph. D. Student | 12 | 10% |
Student > Bachelor | 11 | 9% |
Other | 8 | 7% |
Other | 23 | 19% |
Unknown | 26 | 22% |
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---|---|---|
Agricultural and Biological Sciences | 31 | 26% |
Medicine and Dentistry | 25 | 21% |
Immunology and Microbiology | 6 | 5% |
Biochemistry, Genetics and Molecular Biology | 5 | 4% |
Social Sciences | 4 | 3% |
Other | 17 | 14% |
Unknown | 31 | 26% |