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A metabolic link to skeletal muscle wasting and regeneration

Overview of attention for article published in Frontiers in Physiology, January 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

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245 Mendeley
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Title
A metabolic link to skeletal muscle wasting and regeneration
Published in
Frontiers in Physiology, January 2014
DOI 10.3389/fphys.2014.00032
Pubmed ID
Authors

René Koopman, C. Hai Ly, James G. Ryall

Abstract

Due to its essential role in movement, insulating the internal organs, generating heat to maintain core body temperature, and acting as a major energy storage depot, any impairment to skeletal muscle structure and function may lead to an increase in both morbidity and mortality. In the context of skeletal muscle, altered metabolism is directly associated with numerous pathologies and disorders, including diabetes, and obesity, while many skeletal muscle pathologies have secondary changes in metabolism, including cancer cachexia, sarcopenia and the muscular dystrophies. Furthermore, the importance of cellular metabolism in the regulation of skeletal muscle stem cells is beginning to receive significant attention. Thus, it is clear that skeletal muscle metabolism is intricately linked to the regulation of skeletal muscle mass and regeneration. The aim of this review is to discuss some of the recent findings linking a change in metabolism to changes in skeletal muscle mass, as well as describing some of the recent studies in developmental, cancer and stem-cell biology that have identified a role for cellular metabolism in the regulation of stem cell function, a process termed "metabolic reprogramming."

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 245 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 <1%
United States 2 <1%
Papua New Guinea 1 <1%
Netherlands 1 <1%
United Kingdom 1 <1%
Sweden 1 <1%
Denmark 1 <1%
Slovenia 1 <1%
Unknown 235 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 58 24%
Researcher 39 16%
Student > Master 35 14%
Student > Bachelor 25 10%
Other 11 4%
Other 47 19%
Unknown 30 12%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 67 27%
Agricultural and Biological Sciences 56 23%
Medicine and Dentistry 37 15%
Sports and Recreations 11 4%
Engineering 6 2%
Other 25 10%
Unknown 43 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2016.
All research outputs
#1,936,380
of 23,577,654 outputs
Outputs from Frontiers in Physiology
#1,066
of 14,285 outputs
Outputs of similar age
#23,135
of 309,169 outputs
Outputs of similar age from Frontiers in Physiology
#12
of 106 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,285 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 309,169 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.