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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Effect of oral nitrate supplementation on pulmonary hemodynamics during exercise and time trial performance in normoxia and hypoxia: a randomized controlled trial
|
|---|---|
| Published in |
Frontiers in Physiology, October 2015
|
| DOI | 10.3389/fphys.2015.00288 |
| Pubmed ID | |
| Authors |
Nicolas Bourdillon, Jui-Lin Fan, Barbara Uva, Hajo Müller, Philippe Meyer, Bengt Kayser |
| Abstract |
Hypoxia-induced pulmonary vasoconstriction increases pulmonary arterial pressure (PAP) and may impede right heart function and exercise performance. This study examined the effects of oral nitrate supplementation on right heart function and performance during exercise in normoxia and hypoxia. We tested the hypothesis that nitrate supplementation would attenuate the increase in PAP at rest and during exercise in hypoxia, thereby improving exercise performance. Twelve trained male cyclists [age: 31 ± 7 year (mean ± SD)] performed 15 km time-trial cycling (TT) and steady-state submaximal cycling (50, 100, and 150 W) in normoxia and hypoxia (11% inspired O2) following 3-day oral supplementation with either placebo or sodium nitrate (0.1 mmol/kg/day). We measured TT time-to-completion, muscle tissue oxygenation during TT and systolic right ventricle to right atrium pressure gradient (RV-RA gradient: index of PAP) during steady state cycling. During steady state exercise, hypoxia elevated RV-RA gradient (p > 0.05), while oral nitrate supplementation did not alter RV-RA gradient (p > 0.05). During 15 km TT, hypoxia lowered muscle tissue oxygenation (p < 0.05). Nitrate supplementation further decreased muscle tissue oxygenation during 15 km TT in hypoxia (p < 0.05). Hypoxia impaired time-to-completion during TT (p < 0.05), while no improvements were observed with nitrate supplementation in normoxia or hypoxia (p > 0.05). Our findings indicate that oral nitrate supplementation does not attenuate acute hypoxic pulmonary vasoconstriction nor improve performance during time trial cycling in normoxia and hypoxia. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| New Zealand | 1 | 9% |
| United Kingdom | 1 | 9% |
| Netherlands | 1 | 9% |
| Unknown | 8 | 73% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 45% |
| Scientists | 3 | 27% |
| Science communicators (journalists, bloggers, editors) | 2 | 18% |
| Practitioners (doctors, other healthcare professionals) | 1 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Iran, Islamic Republic of | 1 | 1% |
| United Kingdom | 1 | 1% |
| Unknown | 76 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 16 | 21% |
| Student > Master | 14 | 18% |
| Student > Ph. D. Student | 14 | 18% |
| Researcher | 4 | 5% |
| Lecturer | 3 | 4% |
| Other | 9 | 12% |
| Unknown | 18 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Sports and Recreations | 28 | 36% |
| Medicine and Dentistry | 11 | 14% |
| Agricultural and Biological Sciences | 7 | 9% |
| Nursing and Health Professions | 4 | 5% |
| Biochemistry, Genetics and Molecular Biology | 3 | 4% |
| Other | 7 | 9% |
| Unknown | 18 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 November 2015.
All research outputs
#6,202,906
of 23,310,485 outputs
Outputs from Frontiers in Physiology
#2,819
of 14,045 outputs
Outputs of similar age
#74,610
of 280,523 outputs
Outputs of similar age from Frontiers in Physiology
#30
of 107 outputs
Altmetric has tracked 23,310,485 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 14,045 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,523 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 107 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.