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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The influence of platelet-derived products on angiogenesis and tissue repair: a concise update
|
|---|---|
| Published in |
Frontiers in Physiology, October 2015
|
| DOI | 10.3389/fphys.2015.00290 |
| Pubmed ID | |
| Authors |
Constanza E. Martínez, Patricio C. Smith, Verónica A. Palma Alvarado |
| Abstract |
Platelet degranulation allows the release of a large amount of soluble mediators, is an essential step for wound healing initiation, and stimulates clotting, and angiogenesis. The latter process is one of the most critical biological events observed during tissue repair, increasing the growth of blood vessels in the maturing wound. Angiogenesis requires the action of a variety of growth factors that act in an appropriate physiological ratio to assure functional blood vessel restoration. Platelets release main regulators of angiogenesis: Vascular Endothelial Growth Factors (VEGFs), basic fibroblast growth factor (FGF-2), and Platelet derived growth factors (PDGFs), among others. In order to stimulate tissue repair, platelet derived fractions have been used as an autologous source of growth factors and biomolecules, namely Platelet Rich Plasma (PRP), Platelet Poor Plasma (PPP), and Platelet Rich Fibrin (PRF). The continuous release of these growth factors has been proposed to promote angiogenesis both in vitro and in vivo. Considering the existence of clinical trials currently evaluating the efficacy of autologous PRP, the present review analyses fundamental questions regarding the putative role of platelet derived fractions as regulators of angiogenesis and evaluates the possible clinical implications of these formulations. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 233 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 231 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 31 | 13% |
| Student > Master | 28 | 12% |
| Researcher | 27 | 12% |
| Student > Bachelor | 22 | 9% |
| Student > Postgraduate | 17 | 7% |
| Other | 43 | 18% |
| Unknown | 65 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 87 | 37% |
| Agricultural and Biological Sciences | 17 | 7% |
| Biochemistry, Genetics and Molecular Biology | 16 | 7% |
| Nursing and Health Professions | 7 | 3% |
| Engineering | 7 | 3% |
| Other | 27 | 12% |
| Unknown | 72 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 November 2015.
All research outputs
#18,429,163
of 22,830,751 outputs
Outputs from Frontiers in Physiology
#8,126
of 13,603 outputs
Outputs of similar age
#203,622
of 283,131 outputs
Outputs of similar age from Frontiers in Physiology
#74
of 109 outputs
Altmetric has tracked 22,830,751 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,603 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,131 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 109 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.