Title |
Bubbles Quantified In vivo by Ultrasound Relates to Amount of Gas Detected Post-mortem in Rabbits Decompressed from High Pressure
|
---|---|
Published in |
Frontiers in Physiology, July 2016
|
DOI | 10.3389/fphys.2016.00310 |
Pubmed ID | |
Authors |
Yara Bernaldo de Quirós, Andreas Møllerløkken, Marianne B. Havnes, Alf O. Brubakk, Oscar González-Díaz, Antonio Fernández |
Abstract |
The pathophysiological mechanism of decompression sickness is not fully understood but there is evidence that it can be caused by intravascular and autochthonous bubbles. Doppler ultrasound at a given circulatory location is used to detect and quantify the presence of intravascular gas bubbles as an indicator of decompression stress. In this manuscript we studied the relationship between presence and quantity of gas bubbles by echosonography of the pulmonary artery of anesthetized, air-breathing New Zealand White rabbits that were compressed and decompressed. Mortality rate, presence, quantity, and distribution of gas bubbles elsewhere in the body was examined postmortem. We found a strong positive relationship between high ultrasound bubble grades in the pulmonary artery, sudden death, and high amount of intra and extra vascular gas bubbles widespread throughout the entire organism. In contrast, animals with lower bubble grades survived for 1 h after decompression until sacrificed, and showed no gas bubbles during dissection. |
X Demographics
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 35 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Professor | 3 | 9% |
Researcher | 3 | 9% |
Student > Doctoral Student | 2 | 6% |
Other | 2 | 6% |
Student > Ph. D. Student | 2 | 6% |
Other | 4 | 11% |
Unknown | 19 | 54% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 14% |
Veterinary Science and Veterinary Medicine | 3 | 9% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Economics, Econometrics and Finance | 1 | 3% |
Chemical Engineering | 1 | 3% |
Other | 2 | 6% |
Unknown | 21 | 60% |