Title |
A Disintegrin and Metalloprotease 17 in the Cardiovascular and Central Nervous Systems
|
---|---|
Published in |
Frontiers in Physiology, October 2016
|
DOI | 10.3389/fphys.2016.00469 |
Pubmed ID | |
Authors |
Jiaxi Xu, Snigdha Mukerjee, Cristiane R. A. Silva-Alves, Alynne Carvalho-Galvão, Josiane C. Cruz, Camille M. Balarini, Valdir A. Braga, Eric Lazartigues, Maria S. França-Silva |
Abstract |
ADAM17 is a metalloprotease and disintegrin that lodges in the plasmatic membrane of several cell types and is able to cleave a wide variety of cell surface proteins. It is somatically expressed in mammalian organisms and its proteolytic action influences several physiological and pathological processes. This review focuses on the structure of ADAM17, its signaling in the cardiovascular system and its participation in certain disorders involving the heart, blood vessels, and neural regulation of autonomic and cardiovascular modulation. |
X Demographics
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 48 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 10 | 21% |
Student > Master | 8 | 17% |
Researcher | 7 | 15% |
Student > Ph. D. Student | 7 | 15% |
Other | 2 | 4% |
Other | 4 | 8% |
Unknown | 10 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 10 | 21% |
Agricultural and Biological Sciences | 8 | 17% |
Medicine and Dentistry | 7 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 8% |
Nursing and Health Professions | 1 | 2% |
Other | 6 | 13% |
Unknown | 12 | 25% |