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Evaluation of Salivary and Serum Antioxidant and Oxidative Stress Statuses in Patients with Chronic Periodontitis: A Case-Control Study

Overview of attention for article published in Frontiers in Physiology, March 2017
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Title
Evaluation of Salivary and Serum Antioxidant and Oxidative Stress Statuses in Patients with Chronic Periodontitis: A Case-Control Study
Published in
Frontiers in Physiology, March 2017
DOI 10.3389/fphys.2017.00189
Pubmed ID
Authors

Fatemeh Ahmadi-Motamayel, Mohammad T. Goodarzi, Zohreh Jamshidi, Reza Kebriaei

Abstract

Aim: Local bacteria stimulate polymorphonuclear neutrophils to release reactive oxygen species in periodontitis. Increased levels of oxidative stress play a significant role in the pathogenesis of periodontitis. Therefore, this study aimed to evaluate total salivary and serum antioxidant capacity and malondialdehyde in patients with chronic periodontitis. Materials and methods: Fifty-five healthy subjects and 55 patients with chronic periodontitis, with an age range of 30-50 years, were evaluated. After clinical examination and case selection, unstimulated whole saliva was collected in the morning. Blood samples were taken from the antecubital vein. Total antioxidant capacity and malondialdehyde levels were evaluated by spectrophotometric assay. Data were analyzed with t-test, using Stata.11 software program. Results: The periodontitis group exhibited lower salivary (0.16) and serum (0.36) total antioxidant capacity (P = 0.11) compared to the control group. Mean salivary malondialdehyde levels in the case and control groups were 0.80 ± 0.09 and 0.42 ± 0.08, respectively. The results showed significantly higher levels of salivary and serum malondialdehyde in the periodontitis group. Gender did not have any effect on antioxidant and oxidative stress levels. Conclusion: This study indicated increased levels of salivary and serum oxidative stresses in patients with chronic periodontitis. Total antioxidant capacity was mildly lower in the saliva and serum of these patients. Higher malondialdehyde levels with no changes in antioxidant status can result in systemic and local complications in these patients.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 67 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 12%
Student > Master 6 9%
Student > Ph. D. Student 6 9%
Student > Doctoral Student 5 7%
Other 4 6%
Other 11 16%
Unknown 27 40%
Readers by discipline Count As %
Medicine and Dentistry 27 40%
Biochemistry, Genetics and Molecular Biology 4 6%
Agricultural and Biological Sciences 3 4%
Unspecified 1 1%
Economics, Econometrics and Finance 1 1%
Other 3 4%
Unknown 28 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2017.
All research outputs
#20,412,387
of 22,962,258 outputs
Outputs from Frontiers in Physiology
#9,439
of 13,712 outputs
Outputs of similar age
#269,726
of 309,402 outputs
Outputs of similar age from Frontiers in Physiology
#165
of 214 outputs
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