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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Structure and Function of the Na,K-ATPase Isoforms in Health and Disease
|
|---|---|
| Published in |
Frontiers in Physiology, June 2017
|
| DOI | 10.3389/fphys.2017.00371 |
| Pubmed ID | |
| Authors |
Michael V. Clausen, Florian Hilbers, Hanne Poulsen |
| Abstract |
The sodium and potassium gradients across the plasma membrane are used by animal cells for numerous processes, and the range of demands requires that the responsible ion pump, the Na,K-ATPase, can be fine-tuned to the different cellular needs. Therefore, several isoforms are expressed of each of the three subunits that make a Na,K-ATPase, the alpha, beta and FXYD subunits. This review summarizes the various roles and expression patterns of the Na,K-ATPase subunit isoforms and maps the sequence variations to compare the differences structurally. Mutations in the Na,K-ATPase genes encoding alpha subunit isoforms have severe physiological consequences, causing very distinct, often neurological diseases. The differences in the pathophysiological effects of mutations further underline how the kinetic parameters, regulation and proteomic interactions of the Na,K-ATPase isoforms are optimized for the individual cellular needs. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 473 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 473 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 82 | 17% |
| Student > Bachelor | 65 | 14% |
| Student > Master | 63 | 13% |
| Researcher | 35 | 7% |
| Student > Doctoral Student | 24 | 5% |
| Other | 61 | 13% |
| Unknown | 143 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 101 | 21% |
| Agricultural and Biological Sciences | 53 | 11% |
| Neuroscience | 37 | 8% |
| Medicine and Dentistry | 32 | 7% |
| Chemistry | 22 | 5% |
| Other | 64 | 14% |
| Unknown | 164 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 January 2024.
All research outputs
#2,049,961
of 26,220,821 outputs
Outputs from Frontiers in Physiology
#1,126
of 15,785 outputs
Outputs of similar age
#37,696
of 336,652 outputs
Outputs of similar age from Frontiers in Physiology
#40
of 275 outputs
Altmetric has tracked 26,220,821 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 15,785 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,652 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 275 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.