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Renal Oxygenation in the Pathophysiology of Chronic Kidney Disease

Overview of attention for article published in Frontiers in Physiology, June 2017
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Title
Renal Oxygenation in the Pathophysiology of Chronic Kidney Disease
Published in
Frontiers in Physiology, June 2017
DOI 10.3389/fphys.2017.00385
Pubmed ID
Authors

Zhi Zhao Liu, Alexander Bullen, Ying Li, Prabhleen Singh

Abstract

Chronic kidney disease (CKD) is a significant health problem associated with high morbidity and mortality. Despite significant research into various pathways involved in the pathophysiology of CKD, the therapeutic options are limited in diabetes and hypertension induced CKD to blood pressure control, hyperglycemia management (in diabetic nephropathy) and reduction of proteinuria, mainly with renin-angiotensin blockade therapy. Recently, renal oxygenation in pathophysiology of CKD progression has received a lot of interest. Several advances have been made in our understanding of the determinants and regulators of renal oxygenation in normal and diseased kidneys. The goal of this review is to discuss the alterations in renal oxygenation (delivery, consumption and tissue oxygen tension) in pre-clinical and clinical studies in diabetic and hypertensive CKD along with the underlying mechanisms and potential therapeutic options.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 111 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 22 20%
Student > Master 8 7%
Other 7 6%
Student > Postgraduate 6 5%
Student > Doctoral Student 5 5%
Other 19 17%
Unknown 44 40%
Readers by discipline Count As %
Medicine and Dentistry 31 28%
Nursing and Health Professions 8 7%
Pharmacology, Toxicology and Pharmaceutical Science 6 5%
Biochemistry, Genetics and Molecular Biology 5 5%
Agricultural and Biological Sciences 3 3%
Other 10 9%
Unknown 48 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2017.
All research outputs
#18,556,449
of 22,982,639 outputs
Outputs from Frontiers in Physiology
#8,198
of 13,730 outputs
Outputs of similar age
#241,463
of 315,511 outputs
Outputs of similar age from Frontiers in Physiology
#176
of 274 outputs
Altmetric has tracked 22,982,639 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,730 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,511 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 274 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.