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Cardiac Restoration Stemming From the Placenta Tree: Insights From Fetal and Perinatal Cell Biology

Overview of attention for article published in Frontiers in Physiology, April 2018
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (60th percentile)
  • Good Attention Score compared to outputs of the same age and source (67th percentile)

Mentioned by

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1 X user
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1 Wikipedia page

Citations

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16 Dimensions

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45 Mendeley
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Title
Cardiac Restoration Stemming From the Placenta Tree: Insights From Fetal and Perinatal Cell Biology
Published in
Frontiers in Physiology, April 2018
DOI 10.3389/fphys.2018.00385
Pubmed ID
Authors

Sveva Bollini, Antonietta R. Silini, Asmita Banerjee, Susanne Wolbank, Carolina Balbi, Ornella Parolini

Abstract

Efficient cardiac repair and ultimate regeneration still represents one of the main challenges of modern medicine. Indeed, cardiovascular disease can derive from independent conditions upsetting heart structure and performance: myocardial ischemia and infarction (MI), pharmacological cardiotoxicity, and congenital heart defects, just to name a few. All these disorders have profound consequences on cardiac tissue, inducing the onset of heart failure over time. Since the cure is currently represented by heart transplantation, which is extremely difficult due to the shortage of donors, much effort is being dedicated to developing innovative therapeutic strategies based on stem cell exploitation. Among the broad scenario of stem/progenitor cell subpopulations, fetal and perinatal sources, namely amniotic fluid and term placenta, have gained interest due to their peculiar regenerative capacity, high self-renewal capability, and ease of collection from clinical waste material. In this review, we will provide the state-of-the-art on fetal perinatal stem cells for cardiac repair and regeneration. We will discuss different pathological conditions and the main therapeutic strategies proposed, including cell transplantation, putative paracrine therapy, reprogramming, and tissue engineering approaches.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 18%
Student > Doctoral Student 5 11%
Student > Bachelor 4 9%
Student > Postgraduate 3 7%
Student > Master 3 7%
Other 10 22%
Unknown 12 27%
Readers by discipline Count As %
Medicine and Dentistry 8 18%
Biochemistry, Genetics and Molecular Biology 6 13%
Unspecified 2 4%
Agricultural and Biological Sciences 2 4%
Immunology and Microbiology 2 4%
Other 7 16%
Unknown 18 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2019.
All research outputs
#7,306,728
of 23,045,021 outputs
Outputs from Frontiers in Physiology
#3,517
of 13,790 outputs
Outputs of similar age
#127,605
of 329,180 outputs
Outputs of similar age from Frontiers in Physiology
#145
of 467 outputs
Altmetric has tracked 23,045,021 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 13,790 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,180 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.
We're also able to compare this research output to 467 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.