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Melatonin Relations With Respiratory Quotient Weaken on Acute Exposure to High Altitude

Overview of attention for article published in Frontiers in Physiology, June 2018
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Title
Melatonin Relations With Respiratory Quotient Weaken on Acute Exposure to High Altitude
Published in
Frontiers in Physiology, June 2018
DOI 10.3389/fphys.2018.00798
Pubmed ID
Authors

Marcelo Tapia, Cristian Wulff-Zottele, Nicole De Gregorio, Morin Lang, Héctor Varela, María Josefa Serón-Ferré, Ennio A. Vivaldi, Oscar F. Araneda, Juan Silva-Urra, Hanns-Christian Gunga, Claus Behn

Abstract

High altitude (HA) exposure may affect human health and performance by involving the body timing system. Daily variations of melatonin may disrupt by HA exposure, thereby possibly affecting its relations with a metabolic parameter like the respiratory quotient (RQ). Sea level (SL) volunteers (7 women and 7 men, 21.0 ± 2.04 y) were examined for daily changes in salivary melatonin concentration (SMC). Sampling was successively done at SL (Antofagasta, Chile) and, on acute HA exposure, at nearby Caspana (3,270 m asl). Saliva was collected in special vials (Salimetrics Oral Swab, United Kingdom) at sunny noon (SMCD) and in the absence of blue light at midnight (SMCN). The samples were obtained after rinsing the mouth with tap water and were analyzed for SMC by immunoassay (ELISA kit; IBL International, Germany). RQ measurements (n = 12) were realized with a portable breath to breath metabolic system (OxiconTM Mobile, Germany), between 8:00 PM and 10:00 PM, once at either location. At SL, SMCD, and SMCN values (mean ± SD) were, respectively, 2.14 ± 1.30 and 11.6 ± 13.9 pg/ml (p < 0.05). Corresponding values at HA were 8.83 ± 12.6 and 13.7 ± 16.7 pg/ml (n.s.). RQ was 0.78 ± 0.07 and 0.89 ± 0.08, respectively, at SL and HA (p < 0.05). Differences between SMCN and SMCD (SMCN-SMCD) strongly correlate with the corresponding RQ values at SL (r = -0.74) and less tight at HA (r = -0.37). Similarly, mean daily SMC values (SMC) tightly correlate with RQ at SL (r = -0.79) and weaker at HA (r = -0.31). SMCN-SMCD, as well as, SMC values at SL, on the other hand, respectively, correlate with the corresponding values at HA (r = 0.71 and r = 0.85). Acute exposure to HA appears to loosen relations of SMC with RQ. A personal profile in daily SMC variation, on the other hand, tends to be conserved at HA.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 15%
Student > Ph. D. Student 5 15%
Researcher 4 12%
Student > Master 4 12%
Student > Doctoral Student 3 9%
Other 4 12%
Unknown 8 24%
Readers by discipline Count As %
Medicine and Dentistry 6 18%
Agricultural and Biological Sciences 4 12%
Biochemistry, Genetics and Molecular Biology 2 6%
Social Sciences 2 6%
Sports and Recreations 2 6%
Other 7 21%
Unknown 10 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2018.
All research outputs
#20,527,576
of 23,096,849 outputs
Outputs from Frontiers in Physiology
#9,525
of 13,842 outputs
Outputs of similar age
#288,669
of 329,244 outputs
Outputs of similar age from Frontiers in Physiology
#423
of 528 outputs
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