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Metabolic engineering of the moss Physcomitrella patens to produce the sesquiterpenoids patchoulol and α/β-santalene

Overview of attention for article published in Frontiers in Plant Science, November 2014
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

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2 X users
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2 patents

Citations

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78 Dimensions

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116 Mendeley
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Title
Metabolic engineering of the moss Physcomitrella patens to produce the sesquiterpenoids patchoulol and α/β-santalene
Published in
Frontiers in Plant Science, November 2014
DOI 10.3389/fpls.2014.00636
Pubmed ID
Authors

Xin Zhan, Yu-Hua Zhang, Dong-Fang Chen, Henrik Toft Simonsen

Abstract

The moss Physcomitrella patens, has been genetically engineered to produce patchoulol and β-santalene, two valuable sesquiterpenoid ingredients in the fragrance industry. The highest yield of patchoulol achieved was 1.34 mg/g dry weight. This was achieved by non-targeted transformation of the patchoulol synthase and either a yeast or P. patens HMGR gene under the control of a 35S promoter. Santalene synthase targeted to the plastids yielded 0.039 mg/g dry weight of α/β santalene; cytosolic santalene synthase and 35S controlled HMGR afforded 0.022 mg/g dry weight. It has been observed that the final yield of the fragrance molecules is dependent on the expression of the synthase. This is the first report of heterologous production of sesquiterpenes in moss and it opens up a promising source for light-driven production of valuable fragrance ingredients.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 116 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
France 1 <1%
Germany 1 <1%
Canada 1 <1%
Unknown 112 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 18%
Student > Bachelor 21 18%
Student > Master 21 18%
Researcher 16 14%
Student > Postgraduate 5 4%
Other 12 10%
Unknown 20 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 43 37%
Agricultural and Biological Sciences 37 32%
Chemistry 3 3%
Medicine and Dentistry 3 3%
Engineering 3 3%
Other 2 2%
Unknown 25 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 March 2019.
All research outputs
#4,298,755
of 23,544,633 outputs
Outputs from Frontiers in Plant Science
#2,277
of 21,574 outputs
Outputs of similar age
#59,854
of 366,429 outputs
Outputs of similar age from Frontiers in Plant Science
#24
of 207 outputs
Altmetric has tracked 23,544,633 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 21,574 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 366,429 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 207 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.