Title |
New Era of Studying RNA Secondary Structure and Its Influence on Gene Regulation in Plants
|
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Published in |
Frontiers in Plant Science, May 2018
|
DOI | 10.3389/fpls.2018.00671 |
Pubmed ID | |
Authors |
Xiaofei Yang, Minglei Yang, Hongjing Deng, Yiliang Ding |
Abstract |
The dynamic structure of RNA plays a central role in post-transcriptional regulation of gene expression such as RNA maturation, degradation, and translation. With the rise of next-generation sequencing, the study of RNA structure has been transformed from in vitro low-throughput RNA structure probing methods to in vivo high-throughput RNA structure profiling. The development of these methods enables incremental studies on the function of RNA structure to be performed, revealing new insights of novel regulatory mechanisms of RNA structure in plants. Genome-wide scale RNA structure profiling allows us to investigate general RNA structural features over 10s of 1000s of mRNAs and to compare RNA structuromes between plant species. Here, we provide a comprehensive and up-to-date overview of: (i) RNA structure probing methods; (ii) the biological functions of RNA structure; (iii) genome-wide RNA structural features corresponding to their regulatory mechanisms; and (iv) RNA structurome evolution in plants. |
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Brazil | 3 | 18% |
Russia | 1 | 6% |
Switzerland | 1 | 6% |
India | 1 | 6% |
Mexico | 1 | 6% |
Netherlands | 1 | 6% |
New Zealand | 1 | 6% |
Hong Kong | 1 | 6% |
Other | 0 | 0% |
Unknown | 4 | 24% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 12 | 71% |
Scientists | 5 | 29% |
Mendeley readers
Geographical breakdown
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Unknown | 76 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 18 | 24% |
Researcher | 13 | 17% |
Student > Master | 13 | 17% |
Student > Bachelor | 8 | 11% |
Student > Postgraduate | 3 | 4% |
Other | 8 | 11% |
Unknown | 13 | 17% |
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Chemistry | 5 | 7% |
Immunology and Microbiology | 2 | 3% |
Environmental Science | 2 | 3% |
Other | 3 | 4% |
Unknown | 14 | 18% |