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Increased Low-Frequency Resting-State Brain Activity by High-Frequency Repetitive TMS on the Left Dorsolateral Prefrontal Cortex

Overview of attention for article published in Frontiers in Psychology, December 2017
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Title
Increased Low-Frequency Resting-State Brain Activity by High-Frequency Repetitive TMS on the Left Dorsolateral Prefrontal Cortex
Published in
Frontiers in Psychology, December 2017
DOI 10.3389/fpsyg.2017.02266
Pubmed ID
Authors

Shao-Wei Xue, Yonghu Guo, Wei Peng, Jian Zhang, Da Chang, Yu-Feng Zang, Ze Wang

Abstract

Beneficial effects of repetitive transcranial magnetic stimulation (rTMS) on left dorsolateral prefrontal cortex (DLPFC) have been consistently shown for treating various neuropsychiatrical or neuropsychological disorders, but relatively little is known about its neural mechanisms. Here we conducted a randomized, double-blind, SHAM-controlled study to assess the effects of high-frequency left DLPFC rTMS on resting-state activity. Thirty-eight young healthy subjects received two sessions of either real rTMS (N = 18, 90% motor-threshold; left DLPFC at 20 Hz) or SHAM TMS (N = 20) and functional magnetic resonance imaging scan during rest in 2 days separated by 48 h. Resting-state bran activity was measured with the fractional amplitude of low-frequency fluctuation (fALFF) and functional connectivity (FC). Increased fALFF was found in rostral anterior cingulate cortex (rACC) after 20 Hz rTMS, while no changes were observed after SHAM stimulation. Using the suprathreshold rACC cluster as the seed, increased FC was found in left temporal cortex (stimulation vs. group interaction). These data suggest that high-frequency rTMS on left DLPFC enhances low-frequency resting-state brain activity in the target site and remote sites as reflected by fALFF and FC.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 18%
Student > Bachelor 6 13%
Student > Doctoral Student 5 11%
Student > Postgraduate 4 9%
Student > Master 3 7%
Other 6 13%
Unknown 13 29%
Readers by discipline Count As %
Psychology 9 20%
Neuroscience 8 18%
Medicine and Dentistry 6 13%
Engineering 2 4%
Business, Management and Accounting 1 2%
Other 2 4%
Unknown 17 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2017.
All research outputs
#20,454,971
of 23,011,300 outputs
Outputs from Frontiers in Psychology
#24,409
of 30,257 outputs
Outputs of similar age
#376,525
of 440,922 outputs
Outputs of similar age from Frontiers in Psychology
#496
of 519 outputs
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