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Longitudinal Estimation of the Clinically Significant Change in the Treatment of Major Depression Disorder

Overview of attention for article published in Frontiers in Psychology, August 2018
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Title
Longitudinal Estimation of the Clinically Significant Change in the Treatment of Major Depression Disorder
Published in
Frontiers in Psychology, August 2018
DOI 10.3389/fpsyg.2018.01406
Pubmed ID
Authors

Cristina Cañete-Massé, Maribel Peró-Cebollero, Esteve Gudayol-Ferré, Joan Guàrdia-Olmos

Abstract

Background: Although major depressive disorder is usually treated with antidepressants, only 50-70% of the patients respond to this treatment. This study applied Jacobson and Truax's (1991) methodology (reliable change index, RCI) to a sample of depressive patients being treated with one of two antidepressants to evaluate their functioning and the effect of certain variables such as severity and age. Method: Seventy-three depressive patients medicated with Escitalopram (n = 37) or Duloxetine (n = 36) were assessed using the Hamilton depression rating scale over a 24-week period. Results: They indicate that the RCI stabilizes in an absolute way starting in week 16, and it is not until week 24 that all of the patients become part of the functional population. We found limited statistical significance with respect to the RCI and the external variables. Conclusion: Our study suggests the need to accompany the traditional statistical methodology with some other clinical estimation systems capable of going beyond a simple subtraction between pre and posttreatment values. Hence, it is concluded that RCI estimations could be stronger and more stable than the classical statistical techniques.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 23%
Student > Bachelor 3 14%
Researcher 2 9%
Student > Ph. D. Student 2 9%
Librarian 1 5%
Other 5 23%
Unknown 4 18%
Readers by discipline Count As %
Psychology 8 36%
Medicine and Dentistry 5 23%
Veterinary Science and Veterinary Medicine 1 5%
Nursing and Health Professions 1 5%
Unspecified 1 5%
Other 2 9%
Unknown 4 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 August 2018.
All research outputs
#17,985,001
of 23,096,849 outputs
Outputs from Frontiers in Psychology
#20,892
of 30,483 outputs
Outputs of similar age
#237,739
of 330,723 outputs
Outputs of similar age from Frontiers in Psychology
#583
of 720 outputs
Altmetric has tracked 23,096,849 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
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