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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Human Endogenous Retroviruses as Pathogenic Factors in the Development of Schizophrenia
|
|---|---|
| Published in |
Frontiers in Psychiatry, January 2016
|
| DOI | 10.3389/fpsyt.2015.00183 |
| Pubmed ID | |
| Authors |
Gorjan Slokar, Gregor Hasler |
| Abstract |
Schizophrenia is a complex disorder, characterized by the interplay between genetic and environmental factors. Human endogenous retroviruses (HERVs), genetic elements that originated from infections by exogenous retroviruses millions of years ago, comprise ~8% of the human genome. Here, we provide a comprehensive review of accumulating evidence, detailing HERV aberrancies associated with schizophrenia. Studies examining the genome, transcriptome, and proteome of individuals with schizophrenia provide data that support the association of these viral elements with the disorder. Molecular differences can be found within the central nervous system and peripheral tissues. However, additional studies are needed to substantiate the reported link and to address several discrepancies among previous investigations. We further discuss potentially relevant pathogenic mechanisms to the development of schizophrenia. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 7% |
| Greece | 1 | 7% |
| Unknown | 12 | 86% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 11 | 79% |
| Practitioners (doctors, other healthcare professionals) | 2 | 14% |
| Scientists | 1 | 7% |
Mendeley readers
The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Unknown | 91 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 14% |
| Student > Bachelor | 13 | 14% |
| Researcher | 9 | 10% |
| Student > Ph. D. Student | 9 | 10% |
| Student > Doctoral Student | 7 | 8% |
| Other | 22 | 24% |
| Unknown | 20 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 19 | 20% |
| Biochemistry, Genetics and Molecular Biology | 14 | 15% |
| Agricultural and Biological Sciences | 13 | 14% |
| Neuroscience | 9 | 10% |
| Immunology and Microbiology | 5 | 5% |
| Other | 8 | 9% |
| Unknown | 25 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 294. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2024.
All research outputs
#125,031
of 26,329,145 outputs
Outputs from Frontiers in Psychiatry
#88
of 13,069 outputs
Outputs of similar age
#1,967
of 404,901 outputs
Outputs of similar age from Frontiers in Psychiatry
#1
of 45 outputs
Altmetric has tracked 26,329,145 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,069 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.8. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 404,901 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.