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X Demographics
Mendeley readers
Attention Score in Context
| Title |
From Toxoplasmosis to Schizophrenia via NMDA Dysfunction: Peptide Overlap between Toxoplasma gondii and N-Methyl-d-Aspartate Receptors As a Potential Mechanistic Link
|
|---|---|
| Published in |
Frontiers in Psychiatry, March 2017
|
| DOI | 10.3389/fpsyt.2017.00037 |
| Pubmed ID | |
| Authors |
Guglielmo Lucchese |
| Abstract |
The present work aims at investigating how Toxoplasma gondii (T. gondii) infection may be linked to N-methyl-d-aspartate receptor (NMDAR) dysfunction in schizophrenia and related disorders and puts forward the hypothesis that immune responses against T. gondii may involve NMDARs. Indeed, the analysis of the protozoan proteome and NMDAR subunits for peptide commonalities shows a massive peptide overlap and supports the possibility that anti-T. gondii immune responses raised during active protozoan infection may cross-react with host NMDARs, determining disruption of neural circuits and cognitive deficits. In particular, the NMDA 2D subunit, which is mainly expressed in parvalbumin-positive interneurons, appears to be a hotspot for potential T. gondii-induced cross-reactive immune attacks. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Egypt | 1 | 20% |
| Unknown | 4 | 80% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 51 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 22% |
| Researcher | 6 | 12% |
| Student > Master | 5 | 10% |
| Other | 4 | 8% |
| Student > Bachelor | 4 | 8% |
| Other | 4 | 8% |
| Unknown | 17 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 8 | 16% |
| Biochemistry, Genetics and Molecular Biology | 6 | 12% |
| Medicine and Dentistry | 6 | 12% |
| Immunology and Microbiology | 5 | 10% |
| Agricultural and Biological Sciences | 4 | 8% |
| Other | 3 | 6% |
| Unknown | 19 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 February 2018.
All research outputs
#4,034,860
of 26,555,952 outputs
Outputs from Frontiers in Psychiatry
#2,530
of 13,227 outputs
Outputs of similar age
#68,133
of 326,984 outputs
Outputs of similar age from Frontiers in Psychiatry
#24
of 61 outputs
Altmetric has tracked 26,555,952 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,227 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.9. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,984 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 61 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.