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Electroconvulsive Therapy and Risk of Dementia—A Nationwide Cohort Study in Taiwan

Overview of attention for article published in Frontiers in Psychiatry, September 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

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1 news outlet
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11 X users

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Title
Electroconvulsive Therapy and Risk of Dementia—A Nationwide Cohort Study in Taiwan
Published in
Frontiers in Psychiatry, September 2018
DOI 10.3389/fpsyt.2018.00397
Pubmed ID
Authors

Ching-Wen Chu, Wu-Chien Chien, Chi-Hsiang Chung, Pei-Chun Chao, Hsin-An Chang, Yu-Chen Kao, Yu-Ching Chou, Nian-Sheng Tzeng

Abstract

Background: Electroconvulsive therapy (ECT) is an effective treatment for schizophrenia, bipolar disorder, and major depressive disorder, and a temporary memory loss may occur after ECT. However, the association between ECT in patients with schizophrenia, bipolar disorder, and major depressive disorder, and the risk of dementia is yet to be examined. Objective: This study aimed to clarify as to whether ECT is associated with the risk of dementia after ECT in patients with schizophrenia, bipolar disorder, and major depressive disorder, using Taiwan's National Health Insurance Research Database (NHIRD). Methods: A total of 3,796 enrolled participants (schizophrenia, 46.68%; bipolar disorder, 11.77%; and major depressive disorder, 41.55%) with 994 patients who had received ECT and 2,982 controls matched for sex and age, between January 1, and December 31, 2000, were selected from the NHIRD. After adjusting for confounding factors, Fine and Gray's survival analysis was used to compare the risk of developing dementia during the 10 years of follow-up. Results: Of the study patients, 45 (4.53%) of them developed dementia when compared to 149 (5.0%) in the control group. Fine and Gray's survival analysis revealed that the study patients were not associated with an increased risk of dementia [hazard ratio (HR) = 0.612, 95% confidence interval (CI) = 0.438-1.854, P = 0.325]. After adjusting for sex, age, monthly income, urbanization level, geographic region, and comorbidities, the adjusted HR was 0.633 (95% CI = 0.448 - 1.895, P = 0.304). Conclusion: This study supports that ECT was not associated with the increased risk of dementia in patients with schizophrenia, bipolar disorder, and major depressive disorder, using the NHIRD.

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X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 92 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 20%
Student > Master 16 17%
Researcher 8 9%
Student > Ph. D. Student 8 9%
Student > Postgraduate 7 8%
Other 10 11%
Unknown 25 27%
Readers by discipline Count As %
Psychology 26 28%
Medicine and Dentistry 17 18%
Neuroscience 6 7%
Nursing and Health Professions 3 3%
Social Sciences 3 3%
Other 8 9%
Unknown 29 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2024.
All research outputs
#2,983,594
of 26,375,196 outputs
Outputs from Frontiers in Psychiatry
#1,801
of 13,088 outputs
Outputs of similar age
#56,804
of 350,266 outputs
Outputs of similar age from Frontiers in Psychiatry
#42
of 189 outputs
Altmetric has tracked 26,375,196 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,088 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.9. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 350,266 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 189 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.