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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Pig-Islet Xenotransplantation: Recent Progress and Current Perspectives
|
|---|---|
| Published in |
Frontiers in Surgery, March 2014
|
| DOI | 10.3389/fsurg.2014.00007 |
| Pubmed ID | |
| Authors |
Hai-Tao Zhu, Wan-Li Wang, Liang Yu, Bo Wang |
| Abstract |
Islet xenotransplantation is one prospective treatment to bridge the gap between available human cells and needs of patients with diabetes. Pig represents an ideal candidate for obtaining such available cells. However, potential clinical application of pig islet still faces obstacles including inadequate yield of high-quality functional islets and xenorejection of the transplants. Adequate amounts of available islets can be obtained by selection of a suitable pathogen-free source herd and the development of isolation and purification method. Several studies demonstrated the feasibility of successful preclinical pig-islet xenotransplantation and provided insights and possible mechanisms of xenogeneic immune recognition and rejection. Particularly promising is the achievement of long-term insulin independence in diabetic models by means of distinct islet products and novel immunotherapeutic strategies. Nonetheless, further efforts are needed to obtain much more safety and efficacy data to translate these findings into clinic. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Egypt | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 60 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 11 | 18% |
| Researcher | 11 | 18% |
| Student > Ph. D. Student | 9 | 15% |
| Student > Master | 8 | 13% |
| Student > Postgraduate | 6 | 10% |
| Other | 4 | 7% |
| Unknown | 12 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 14 | 23% |
| Biochemistry, Genetics and Molecular Biology | 12 | 20% |
| Medicine and Dentistry | 6 | 10% |
| Engineering | 5 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
| Other | 6 | 10% |
| Unknown | 15 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 December 2018.
All research outputs
#1,362,897
of 22,749,166 outputs
Outputs from Frontiers in Surgery
#31
of 2,811 outputs
Outputs of similar age
#14,687
of 223,836 outputs
Outputs of similar age from Frontiers in Surgery
#2
of 9 outputs
Altmetric has tracked 22,749,166 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,811 research outputs from this source. They receive a mean Attention Score of 2.3. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 223,836 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.