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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Chloride:Sodium Ratio May Accurately Predict Corrected Chloride Disorders and the Presence of Unmeasured Anions in Dogs and Cats
|
|---|---|
| Published in |
Frontiers in Veterinary Science, August 2017
|
| DOI | 10.3389/fvets.2017.00122 |
| Pubmed ID | |
| Authors |
Robert Goggs, Marc Myers, Sage De Rosa, Erik Zager, Daniel J. Fletcher |
| Abstract |
Disorders of chloride and mixed acid-base disturbances are common in veterinary emergency medicine. Rapid identification of these alterations and the presence of unmeasured anions aid prompt patient assessment and management. This study aimed to determine in dogs and cats if site-specific reference values for [Cl(-)]:[Na(+)] ratio and [Na(+)] - [Cl(-)] difference accurately identify corrected chloride abnormalities and to evaluate the predictive ability of the [Cl(-)]:[Na(+)] ratio for the identification of unmeasured anions. A database containing 33,117 canine, and 7,604 feline blood gas and electrolyte profiles was generated. Institution reference intervals were used to calculate site-specific reference values for the [Cl(-)]:[Na(+)] ratio and the [Na(+)] - [Cl(-)] difference. Contingency tables were used to assess the ability of these values to correctly identify corrected chloride disorders. Unmeasured anions were estimated by calculating strong ion gap (SIG). Continuous variables were compared using the Mann-Whitney U test. Correlations between continuous variables were assessed using Spearman's rho (rs). In dogs, site-specific reference values for the [Cl(-)]:[Na(+)] ratio correctly identified 94.6% of profiles as hyper-, normo-, or hypochloremic. For dogs with normal sodium concentrations, site-specific reference values for the [Na(+)] - [Cl(-)] difference correctly identified 97.0% of profiles. In dogs with metabolic acidosis (base deficit > 4.0), [Cl(-)]:[Na(+)] ratio and SIG were moderately but significantly negatively correlated (rs -0.592, P < 0.0001). SIG was significantly greater in dogs with metabolic acidosis and hypochloremia compared to those without hypochloremia (P < 0.0001). In cats, site-specific reference values for the [Cl(-)]:[Na(+)] ratio correctly identified 93.3% of profiles as hyper-, normo-, or hypochloremic, while site-specific reference values for [Na(+)] - [Cl(-)] difference correctly identified 95.1% of profiles. In cats with metabolic acidosis [Cl(-)]:[Na(+)] ratio and SIG were moderately significantly negatively correlated (rs -0.730, P < 0.0001). SIG was significantly greater in cats with metabolic acidosis and hypochloremia compared to those without hypochloremia (P < 0.0001). Site-specific values for [Cl(-)]:[Na(+)] ratio and [Na(+)] - [Cl(-)] difference accurately identify corrected chloride disorders in both dogs and cats and may aid identification of the presence of unmeasured anions. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 20 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Professor > Associate Professor | 4 | 20% |
| Other | 3 | 15% |
| Student > Ph. D. Student | 3 | 15% |
| Student > Bachelor | 3 | 15% |
| Student > Master | 3 | 15% |
| Other | 1 | 5% |
| Unknown | 3 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Veterinary Science and Veterinary Medicine | 9 | 45% |
| Medicine and Dentistry | 2 | 10% |
| Linguistics | 1 | 5% |
| Biochemistry, Genetics and Molecular Biology | 1 | 5% |
| Agricultural and Biological Sciences | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 5 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2017.
All research outputs
#17,910,703
of 22,996,001 outputs
Outputs from Frontiers in Veterinary Science
#3,507
of 6,310 outputs
Outputs of similar age
#227,733
of 317,618 outputs
Outputs of similar age from Frontiers in Veterinary Science
#39
of 56 outputs
Altmetric has tracked 22,996,001 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,310 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,618 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.