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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Pharmacokinetics of Conventional and Long-Acting Oxytetracycline Preparations in Kilis Goat
|
|---|---|
| Published in |
Frontiers in Veterinary Science, December 2017
|
| DOI | 10.3389/fvets.2017.00229 |
| Pubmed ID | |
| Authors |
İbrahim Aktas, Ender Yarsan |
| Abstract |
The pharmacokinetics of conventional and long-acting (LA) oxytetracycline (OTC), widely used broad-spectrum antibacterial drugs in veterinary medicine, were evaluated in Kilis goats at single dosage of 20 mg/kg body weight (bw). A total of 21 goats were divided into three groups: intravenous (Group I) and intramuscular (IM) (Group II) administration of the conventional formulation and IM administration of the LA formulation (Group III). Blood samples were taken at 0.25, 0.5, 1, 2, 4, 8, 12, 24, 36, 48, 60, 72, and 96 h; and OTC analysis was performed by HPLC. For Group III and Group II, time to reach maximal plasma drug concentration (Tmax) was 0.6 ± 0.28 and 0.46 ± 0.09 h and maximal plasma drug concentrations (Cmax) were 8.72 ± 2.47 μg/ml and 13.57 ± 5.83 μg/ml, respectively. In Group I, C0 concentration was found to be 63.51 ± 11.59 μg/ml. The elimination times (T1/2) were 10.84 ± 3.20, 27.96 ± 11.66, and 10.47 ± 1.30 h; and AUC were 115 ± 29.12, 96.44 ± 9.49, and 80.86 ± 12.76 μg/ml/h for Group I; Group II, and Group III, respectively. Bioavailability by IM administration were 69.71% for the conventional OTC and 83.15% for the LA OTC. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 26 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 19% |
| Student > Master | 4 | 15% |
| Student > Doctoral Student | 4 | 15% |
| Lecturer | 1 | 4% |
| Other | 1 | 4% |
| Other | 0 | 0% |
| Unknown | 11 | 42% |
| Readers by discipline | Count | As % |
|---|---|---|
| Veterinary Science and Veterinary Medicine | 5 | 19% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
| Biochemistry, Genetics and Molecular Biology | 1 | 4% |
| Agricultural and Biological Sciences | 1 | 4% |
| Economics, Econometrics and Finance | 1 | 4% |
| Other | 4 | 15% |
| Unknown | 13 | 50% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 January 2018.
All research outputs
#17,923,510
of 23,012,811 outputs
Outputs from Frontiers in Veterinary Science
#3,509
of 6,324 outputs
Outputs of similar age
#308,869
of 440,933 outputs
Outputs of similar age from Frontiers in Veterinary Science
#41
of 65 outputs
Altmetric has tracked 23,012,811 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,324 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 440,933 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.