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Single-Cell Transcription Mapping of Murine and Human Mammary Organoids Responses to Female Hormones

Overview of attention for article published in Journal of Mammary Gland Biology and Neoplasia, January 2024
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#18 of 393)
  • High Attention Score compared to outputs of the same age (88th percentile)

Mentioned by

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24 X users

Citations

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1 Dimensions

Readers on

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11 Mendeley
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Title
Single-Cell Transcription Mapping of Murine and Human Mammary Organoids Responses to Female Hormones
Published in
Journal of Mammary Gland Biology and Neoplasia, January 2024
DOI 10.1007/s10911-023-09553-x
Pubmed ID
Authors

Jenelys Ruiz Ortiz, Steven M. Lewis, Michael Ciccone, Deeptiman Chatterjee, Samantha Henry, Adam Siepel, Camila O. dos Santos

Abstract

During female adolescence and pregnancy, rising levels of hormones result in a cyclic source of signals that control the development of mammary tissue. While such alterations are well understood from a whole-gland perspective, the alterations that such hormones bring to organoid cultures derived from mammary glands have yet to be fully mapped. This is of special importance given that organoids are considered suitable systems to understand cross species breast development. Here we utilized single-cell transcriptional profiling to delineate responses of murine and human normal breast organoid systems to female hormones across evolutionary distinct species. Collectively, our study represents a molecular atlas of epithelial dynamics in response to estrogen and pregnancy hormones.

X Demographics

X Demographics

The data shown below were collected from the profiles of 24 X users who shared this research output. Click here to find out more about how the information was compiled.
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 3 27%
Student > Ph. D. Student 3 27%
Professor 1 9%
Other 1 9%
Unknown 3 27%
Readers by discipline Count As %
Unspecified 3 27%
Biochemistry, Genetics and Molecular Biology 3 27%
Medicine and Dentistry 1 9%
Unknown 4 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 February 2024.
All research outputs
#2,644,229
of 26,294,065 outputs
Outputs from Journal of Mammary Gland Biology and Neoplasia
#18
of 393 outputs
Outputs of similar age
#41,221
of 374,931 outputs
Outputs of similar age from Journal of Mammary Gland Biology and Neoplasia
#1
of 4 outputs
Altmetric has tracked 26,294,065 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 393 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.5. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 374,931 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them