Title |
Transcription factories
|
---|---|
Published in |
Frontiers in Genetics, January 2012
|
DOI | 10.3389/fgene.2012.00221 |
Pubmed ID | |
Authors |
Dietmar Rieder, Zlatko Trajanoski, James G. McNally |
Abstract |
There is considerable evidence that transcription does not occur homogeneously or diffusely throughout the nucleus, but rather at a number of specialized, discrete sites termed transcription factories. The factories are composed of ~4-30 RNA polymerase molecules, and are associated with many other molecules involved in transcriptional activation and mRNA processing. Some data suggest that the polymerase molecules within a factory remain stationary relative to the transcribed DNA, which is thought to be reeled through the factory site. There is also some evidence that transcription factories could help organize chromatin and nuclear structure, contributing to both the formation of chromatin loops and the clustering of active and co-regulated genes. |
X Demographics
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 2 | <1% |
Germany | 1 | <1% |
Switzerland | 1 | <1% |
France | 1 | <1% |
South Africa | 1 | <1% |
Israel | 1 | <1% |
Canada | 1 | <1% |
Denmark | 1 | <1% |
Korea, Republic of | 1 | <1% |
Other | 1 | <1% |
Unknown | 202 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 51 | 24% |
Researcher | 40 | 19% |
Student > Master | 32 | 15% |
Student > Bachelor | 20 | 9% |
Student > Doctoral Student | 10 | 5% |
Other | 31 | 15% |
Unknown | 29 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 81 | 38% |
Biochemistry, Genetics and Molecular Biology | 72 | 34% |
Physics and Astronomy | 8 | 4% |
Medicine and Dentistry | 7 | 3% |
Computer Science | 4 | 2% |
Other | 10 | 5% |
Unknown | 31 | 15% |