Microbial Metabolite Sodium Butyrate Attenuates Cartilage Degradation by Restoring Impaired Autophagy and Autophagic Flux in Osteoarthritis Development

RT @renesugar: https://t.co/HENb4FdZJ5 "In conclusion, NaB could attenuate OA progression by restoring impaired autophagy and autophagic f…

https://t.co/HENb4FdZJ5 "both in vitro and in vivo, implying that NaB could represent a novel therapeutic approach for OA."

https://t.co/HENb4FdZJ5 "In conclusion, NaB could attenuate OA progression by restoring impaired autophagy and autophagic flux via the phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) pathway,"

https://t.co/HENb4FdZJ5 "which indicated that the protective effects of NaB against OA were partially governed by the enhancement of autophagy to restrain the formation of inflammatory mediators and ROS and regulate cell cycle progression and apoptosis in