RT @renesugar: https://t.co/jn9Pzn4u6Z "In other studies, hyperoxia attenuated the expression of UPR mediators GRP78 and PDIA3."
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https://t.co/jn9Pzn4u6Z "In other studies, hyperoxia attenuated the expression of UPR mediators GRP78 and PDIA3."
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https://t.co/jn9Pzn4u6Z "and lowering the viral titer in the airways of mice infected with IAV." "Although GRP78 is largely localized to the ER, under ER stress conditions, a small fraction of the chaperone is translocated to the cell surface."
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https://t.co/jn9Pzn4u6Z "In addition, the ER stress inhibitors, tauroursodeoxycholic acid and 4-phenylbutyrate, are effective at, respectively, reducing the expression of viral proteins in human tracheobronchial epithelial cells"