@TomKindlon @Joulukuu2013 L-Cn has an immunosuppressant effect. Good for autoimmune conditions but not for viral persistence. "excess L-Cn Impairs Immune Responses" But: "L-Cn Promotes IL-10 Production by Treg and the Expression of Inhibitory Receptors on
https://t.co/ftrKzDkTYi "for SNP rs179982 (gene CPT2), patients with GG genotype had lower plasma L-Cn levels than those with AA genotype"
https://t.co/ftrKzDkTYi "Moreover, a variant in CPT2 (rs1799821) was confirmed to be associated with L-Cn levels as well as complete response in CHB patients following Peg-IFNα antiviral therapy."
https://t.co/ftrKzDkTYi "It also down-regulated the proliferation and IgG production of B cells. Notably, L-Cn enhanced IL-10 secretion from regulatory T cells and up-regulated the expression of inhibitory receptors on T cells."