@doc4care Thanks! Published a follow-up paper discussing mechanisms of immune-enhanced disease that was circulated by the FDA during vaccine evaluation. Amid phrases like “warp speed” it was a relief that all the ones authorized in the US encode a pre-fusi
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RT @hussmanjp: @yunlong_cao Appreciate your work, esp in relation to RBD. Given its immunodominance and mutability, it’s notable that next…
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@yunlong_cao Appreciate your work, esp in relation to RBD. Given its immunodominance and mutability, it’s notable that next gen boosters present the prefusion spike - which largely conceals RBD, and McLellan’s group has reported to improve and broaden immu
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Pleased both Pfizer & Moderna bivalent (Wuhan-1 & Omicron) boosters use prefusion spike design (👏 @McLellan_Lab) and not S-RBD in full Monty. More discussion in final section of my paper. https://t.co/4wyKJY6OdC Pfizer:https://t.co/lMFeGL6z2a Moder