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RT @Atelfo: Found another paper that suggests linker stability (row C) doesn't correlate well with preclinical efficacy (row B). What's imp…
RT @Atelfo: Found another paper that suggests linker stability (row C) doesn't correlate well with preclinical efficacy (row B). What's imp…
Found another paper that suggests linker stability (row C) doesn't correlate well with preclinical efficacy (row B). What's important is that the payload hits a threshold concentration in the tumour that maximizes efficacy (row E) source: https://t.co/j4x
New Research: Linker Design Impacts Antibody-Drug Conjugate Pharmacokinetics and Efficacy via Modulating the Stability and Payload Release Efficiency https://t.co/thnHsR7sO3 #pharmacology