Title |
New drugs and combinations for the treatment of soft-tissue sarcoma: a review
|
---|---|
Published in |
Cancer Management and Research, November 2012
|
DOI | 10.2147/cmar.s23257 |
Pubmed ID | |
Authors |
Neeta Somaiah, Margaret von Mehren |
Abstract |
Sarcomas are a heterogeneous group of solid tumors arising from either soft tissues or bone, accounting for approximately 1% of all cancers in adults. Management of these diseases has changed little over the past 10 years, with the exception of treatment of gastrointestinal stromal tumors. Reasons for this stagnation include multiple histologies commonly grouped together in clinical trials limiting the understanding of benefit of treatment and limited investigation of molecular targeted therapies. More recently, advances in molecular pathogenesis, the advent of novel and targeted therapeutics, and increasing collaborations between sarcoma investigators has helped move the field forward in the right direction. Here, we review the recent data on novel agents tested for the management of adult soft-tissue sarcomas, excluding gastrointestinal stromal tumors. |
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Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 6 | 86% |
Unknown | 1 | 14% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 86% |
Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Unknown | 53 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 19% |
Student > Ph. D. Student | 8 | 15% |
Student > Bachelor | 8 | 15% |
Other | 7 | 13% |
Student > Master | 7 | 13% |
Other | 9 | 17% |
Unknown | 5 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 20 | 37% |
Agricultural and Biological Sciences | 12 | 22% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 7% |
Business, Management and Accounting | 3 | 6% |
Nursing and Health Professions | 3 | 6% |
Other | 6 | 11% |
Unknown | 6 | 11% |