https://t.co/J1Ce7pCDb7 "Peramivir contains an unusual 5-membered ring but retains high potency as its functional groups bind in a similar way to oseltamivir and zanamivir."
3,847 followers
3,847 followers
https://t.co/J1Ce7pCDb7 "Each of these drugs form extensive contacts with conserved residues in the SA active site, which out-compete terminal sialic acid residues on the host glycans, thus inhibiting the release of virus progeny from infected cells."
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Sialidase and Sialyltransferase Inhibitors: Targeting Pathogenicity and Disease https://t.co/J1Ce7pCDb7
2,510 followers
New Research: Sialidase and Sialyltransferase Inhibitors: Targeting Pathogenicity and Disease https://t.co/Jv13w1NkAY #MolBioSci