RT @IronBiologyBot: Paper alert: Ferroptosis: A Trigger of Proinflammatory State Progression to Immunogenicity in Necroinflammatory Diseas…
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297 followers
Paper alert: Ferroptosis: A Trigger of Proinflammatory State Progression to Immunogenicity in Necroinflammatory Disease https://t.co/tiCV8eroR1 #IronBiology
34,934 followers
2)Ferroptosis:non-apoptotic cell death-⬆️lipid peroxidation,overload iron,ischemia/reperfusion (I/R)injury;surplus reactive oxygen species (ROS);imbalanced redox reaction;decrease glutathione synthesis,inaction enzyme glutathione peroxidase 4 (GPX4).Ferrop
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Ferroptosis:Trigger Proinflam.State Progress to Immunogenicity in Necroinflam.Dis:Programmed necrosis:necrosis,pyroptosis,ferroptosis-⬆️immunogenic vs apoptosis;⬆️inflam.cytokines,danger-asso molec.pattern(DAMPs),necroinflam;Ferroptosis-non-apoptotic death