@kevinault @CaulfieldTim So a shift happened (potentially as a result of the vax?) already and vax had to adapt for add'l valents. It's Nature--always seeks to correct itself--it seems like this is likely to happen again. https://t.co/gif24IrNLf
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@CaulfieldTim Too early to be beating the drums. ARR is incredibly small and still determined in age groups under the normal demographics for cervical cancer. We can revisit this again in 20 years when we're sure that antigenic replacement isn't a factor.
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@CaulfieldTim @CarlaKJohnson Still think it's too early to get excited. ARR are exceedingly low. Once we see if cervical cancer rates (not CIN III) drop in the 35-44 age group, then we can get excited. Until then, serotype distribution changes may wipe ou
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