@perceptabrain Just reading about Sanfilippo Syndrome and stumbled upon this article. The Unifying Hypothesis of Alzheimer’s Disease: Heparan Sulfate Proteoglycans/Glycosaminoglycans Are Key as First Hypothesized Over 30 Years Ago. (1) https://t.co/RQp82U3
@resiapretorius @polybioRF @PutrinoLab @MBVanElzakker @jfvaughnmd09 @doctorasadkhan An interesting read for you and your LC team. https://t.co/q4iMfnSOA8 We believe this WB heparin apheresis could be a maintenance treatment for amyloidogenesis. Acting as
"Brain aging leads to changes in HSPGs, including newly identified splice variants leading to ⬆️ HS GAG sulfation in the AD brain. All of these events lead to the new "Unifying Hypothesis of Alzheimer's disease", further implicating HSPGs /HS GAGs as key"
RT @FrontNeurosci: New Research: The Unifying Hypothesis of Alzheimer’s Disease: Heparan Sulfate Proteoglycans/Glycosaminoglycans Are Key a…