RT @bengreenfield: Cotinine is a potent nicotine substitute with unique and quite noticeable effects on alertness. I took 150mg today at 5a…
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Cotinine is a potent nicotine substitute with unique and quite noticeable effects on alertness. I took 150mg today at 5am and just now wearing off: https://t.co/YveCGnZmKX - anyone else have experience or comments on cotinine?
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コチニン cotinine は主にその代謝遺伝子を知る課題から知ったけど、これもニコチンと同じシナプス受容体と結びついて様々な神経・精神への効果を齎すとな。禁煙薬がよく効かないのはニコチンにしか注目してなかったから「かもしれない」という視点をこの論文で知ったにゃご https://t.co/M70CTSUIO7 https://t.co/K2zr3U2sgl
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@ChaunceyGardner "Nicotine is a highly lipophilic compound...and accumulates in the brain" https://t.co/phoNLCgF20 "Nicotine is a tertiary amine, and its un-ionized form is highly lipophilic, whereas cotinine is more polar and less lipophilic" https://t.c