GC | Editorial: B Cell Activation and Differentiation: New Perspectives on an Enduring Topic https://t.co/AFbvfZWXZA
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2)GC-dysregul Bcell-autoimmunity.Abs-Bcell- interact wth CD4+/pre-Tfhcell:T-B border & fully dev Tfhcell in follicle;regul-affinty BCR to Ag-selectn Bcell-extrafollic or GC;differtn to Ab-secret(ASC)& mBcell expr ⬆️/⬇️affinty BCR,Tfhcell,BCR,crossl
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Bcell Activ-Differtn:B lympho-long-live PC,mBcell,spec Abs of switch Ig isotype(IgG,IgA,IgE):innate/adaptv immune,activ/fine-tune-signal R & conventnl protein(integrins/nuclear R).Bcell alter signal transducer,transcriptn F,reshape epigenome,transcript
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RT @FrontImmunol: New Research: Editorial: B Cell Activation and Differentiation: New Perspectives on an Enduring Topic https://t.co/VA4j4o…