RT @EnCouRage_FMHHS: A simple switch of stereochemistry can alter the selectivity towards LIMK1 or LIMK2 of pyrrolopyrimidine-based inhibit…
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A simple switch of stereochemistry can alter the selectivity towards LIMK1 or LIMK2 of pyrrolopyrimidine-based inhibitors - Dr Ariawan explains #medicinalchemistry #organicchemistry #EnCouRageMQ #MQHealth https://t.co/LQo30C9qU2
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New Research: The Nature of Diamino Linker and Halogen Bonding Define Selectivity of Pyrrolopyrimidine-Based LIMK1 Inhibitors: The LIM-domain kinase (LIMK) family consists of two isoforms, LIMK1 and LIMK2, which are highly homologous, making… https://t.co/