@LidskyPeter @TSchmauck Indeed, yet the mutational rate in the germline will always be lower. Fig 1: https://t.co/JlmoPGgzMU
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@rajivmccoy @jkpritch Not same mechanism, but somatic mutation sequencing studies in the last 5 years or so indicate that the DNA synthesis machinery is also extra-sloppy in the first few cell divisions. https://t.co/xTFqwWpoux
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The #Dynamics of #Somatic #Mutagenesis During #Life in #Humans https://t.co/n2YSn7SOa2 #cancer
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I don't want to be that guy who complains about "gatekeeping," but this is a great article and it's kinda bullshit that it isn't on Pubmed. https://t.co/xTFqwWpoux