発癌 Histone H3特異chaperone複合体の動的活性 https://t.co/TEAoWUhgmS Histone chaperone発現調節不全up-and down-regulationが腫瘍進行に関与? 特にCAF-1異所性発現はchromatinの正規H3.1変異とH3変異間の切り替え促進、染色状態を損ない、染色体の不安定性を起こし、🧬転写に影響、発癌に寄与?
3,356 followers
144 followers
RT @Nucleosome_Bot: Dynamic Activity of Histone H3-Specific Chaperone Complexes in Oncogenesis https://t.co/CAmUtC2Z38
4,911 followers
Dynamic Activity of Histone H3-Specific Chaperone Complexes in Oncogenesis https://t.co/CAmUtC2Z38
6,549 followers
New research: Dynamic Activity of Histone H3-Specific Chaperone Complexes in Oncogenesis: Canonical histone H3.1 and variant H3.3 deposit at different sites of the chromatin via distinct histone chaperones. Histone H3.1 relies on chaperone… https://t.co/r8