RT @keisuke4713: https://t.co/PtKmC5W2rx cGAS-STING 細胞質の外来DNA,RNA感知応答 *💉 cGAS 核にも存在 STING依存細胞質DNA受容体,病原DNA,RNA,自己DNAを認識応答PRR(宿主pattern認識受容…
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https://t.co/PtKmC5W2rx cGAS-STING 細胞質の外来DNA,RNA感知応答 *💉 cGAS 核にも存在 STING依存細胞質DNA受容体,病原DNA,RNA,自己DNAを認識応答PRR(宿主pattern認識受容体) GTP,ATPと結合→環状GMP-AMP(cGAMP)⬆️ STING⬆️ 小胞体(ER)からSTINGは外来DNA,RNA応答 IRF3かNF-kBリン酸化→自然免疫応答 https://t.co/KiSQgQSqyU
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@Smalling5Jerry @robinmonotti The DNA doesn't have to enter the nucleus This is not like "oh it'll be fine" https://t.co/XRVhnfdDNV https://t.co/z02Skk8pCP
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RT @_HeartofGrace_: 🚨 The cGAS-STING pathway in humans, can detect and be activated by pieces of DNA, bacterial DNA, AND RNA (all are in th…