Proteolytic Cleavage of the Extracellular Domain Affects Signaling of Parathyroid Hormone 1 Receptor https://t.co/TYEPvJdP3X
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415 followers
Intriguing paper identifying the stretch of extracellular portion of PTH-receptor cut by a protease (likely MMP) and consequences for pathway specific (Gs vs Gq) signaling! https://t.co/dDwexLHydJ (1/3)
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RT @ChristophKlenk: Finally out @FrontEndocrinol! Check out our recent discovery that protease cleaveage modulates #signaling selectivity o…
887 followers
RT @ChristophKlenk: Finally out @FrontEndocrinol! Check out our recent discovery that protease cleaveage modulates #signaling selectivity o…