Thomas J. FitzGerald, Maryann Bishop-Jodoin, Walter R. Bosch, Walter J. Curran, David S. Followill, James M. Galvin, Richard Hanusik, Steven R. King, Michael V. Knopp, Fran Laurie, Elizabeth O'Meara, Jeff M. Michalski, Joel H. Saltz, Mitchell D. Schnall, Lawrence Schwartz, Kenneth Ulin, Ying Xiao, Marcia Urie
Abstract
The National Cancer Institute clinical cooperative groups have been instrumental over the past 50 years in developing clinical trials and evidence-based process improvements for clinical oncology patient care. The cooperative groups are undergoing a transformation process as we further integrate molecular biology into personalized patient care and move to incorporate international partners in clinical trials. To support this vision, data acquisition and data management informatics tools must become both nimble and robust to support transformational research at an enterprise level. Information, including imaging, pathology, molecular biology, radiation oncology, surgery, systemic therapy, and patient outcome data needs to be integrated into the clinical trial charter using adaptive clinical trial mechanisms for design of the trial. This information needs to be made available to investigators using digital processes for real-time data analysis. Future clinical trials will need to be designed and completed in a timely manner facilitated by nimble informatics processes for data management. This paper discusses both past experience and future vision for clinical trials as we move to develop data management and quality assurance processes to meet the needs of the modern trial.
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 May 2014.
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#16,109,035
of 25,461,852 outputs
Outputs from Frontiers in oncology
#5,672
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#180,681
of 289,411 outputs
Outputs of similar age from Frontiers in oncology
#105
of 328 outputs
Altmetric has tracked 25,461,852 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,544 research outputs from this source. They receive a mean Attention Score of 3.0. This one has gotten more attention than average, scoring higher than 71% of its peers.
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We're also able to compare this research output to 328 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
