RT @nehakprasad9: The toxicity of hydroxamate was the downfall of antibacterial clinical candidate ACHN-975 (LpxC inhibitor). This paper fe…
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RT @nehakprasad9: The toxicity of hydroxamate was the downfall of antibacterial clinical candidate ACHN-975 (LpxC inhibitor). This paper fe…
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The toxicity of hydroxamate was the downfall of antibacterial clinical candidate ACHN-975 (LpxC inhibitor). This paper features a great strategy (fraction based drug discovery) to find novel non-hydroxamate zinc-coordinating groups for LpxC inhibition. htt
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#papworthauthors new publication: Using Structure-guided Fragment-Based Drug Discovery to Target Pseudomonas aeruginosa Infections in Cystic Fibrosis. https://t.co/QAvUv8jEKV. @RoyalPapworth @RoyalPapRes