https://t.co/Yi1gDtJ0SR "Casey reported that the G304K mutant STRA6 protein is mislocalized and has severely reduced vitamin A uptake activity."
4,000 followers
4,000 followers
https://t.co/Yi1gDtJ0SR "Interestingly, a missense double-nucleotide polymorphism (g.1157G>A and g.1156G>A; p.Gly304Lys, rs151341424) in STRA6 was found in the Irish Traveler family with isolated microphthalmia and coloboma (MCOPCB8), a rare autosom
4,000 followers
https://t.co/Yi1gDtJ0SR "STRA6 is ubiquitously expressed, and its expression status is regulated by the retinoid metabolisms."
4,000 followers
https://t.co/Yi1gDtJ0SR "Delivery of retinol to the target cells is mediated by the binding of retinol-bound- (holo-) RBP and an RBP receptor called STRA6 (Stimulated by Retinoic Acid 6)."