Low Levels of Factor H Family Proteins During Meningococcal Disease Indicate Systemic Processes Rather Than Specific Depletion by Neisseria meningitidis

RT @FPoppelaars: 16.) The first specific measurement of FH and all FHRs in an #infectious disease has only recently been reported, namely…

16.) The first specific measurement of FH and all FHRs in an #infectious disease has only recently been reported, namely in meningococcal disease: ➡️ https://t.co/YDirEdQl7b Moreover,⬇️levels of FH in🩸confers protection from meningococcal disease: ➡️ ht

PAPER OF THE WEEK N. meningitidis evades complement by 'hijacking' factor H (FH). Van Beek et al showed that the circulating levels of all FH family proteins are equally⬇️during meningococcal disease (MD), but loss of FH associated with severity. Read it👇