Part 2: CBP, CREB-binding protein; HDAC, #histone deacetylase; HAC, histone acetylase; IRS-1, insulin receptor substrate 1; TrkB, tropomyosin receptor kinase B; CREB, FOXO3a, transcription factors; H3K4, histone H3 lysine 9. https://t.co/fjk1N20e7S #MedTw
Part 1: Maternal high-fat diet downregulates #BDNF due to chromatin remodeling and increased histone deacetylation on the Bdnf promotor. BDNF/Bdnf, brain-derived neurotrophic factor; https://t.co/fjk1N20e7S #HealthForAll #neuroscience #MedTwitter #health
Maternal HFD-induced gut and breastmilk dysbiosis and its impact on offspring gut microbiota in mouse models (A) and human individuals (B). https://t.co/fjk1N20e7S #MentalHealthAwareness #HealthForAll #neuroscience #MedTwitter #healthyfood #Nutrition http
Part 3: TNF-α, tumor necrosis factor-alpha; CRP, C-reactive protein; CCL2, chemokine (C–C motif) ligand; IFN-γ, interferon-gamma. https://t.co/fjk1N20e7S #MentalHealthAwareness #HealthForAll #neuroscience #MedTwitter #healthyfood #Nutrition https://t.co/Y