New perspectives on the regulation of germinal center reaction via αvβ8- mediated activation of TGFβ

RT @CIRI_Bcell_lab: @SebastienThis (now @MelicharLab) & @HelenaPaidassi published a review @FrontImmunol on the regulation of the #Germinal…

@SebastienThis (now @MelicharLab) & @HelenaPaidassi published a review @FrontImmunol on the regulation of the #GerminalCenter reaction by TGFβ, highlighting the role of its activation by αvβ8 integrin, which is currently underestimated in the field h

GC | New perspectives on the regulation of germinal center reaction via αvβ8- mediated activation of TGFβ https://t.co/HfcMMChXpT

New perspectives on regulation of GC reaction via αvβ8- mediated activation of TGFβ: Transforming growth factor-β (TGFβ) long-known modulator of immune responses,& contradictory effects on Bcells. In cytokines,TGFβ is produced & secreted in latent